Warfarin Related Kidney Damage: A Confusing Case of Thrombophlebitis Masquerading as Infection
Warfarin Related Kidney Damage: A Confusing Case of Thrombophlebitis Masquerading as Infection
Blog Article
Anticoagulant-related nephropathy (ARN) is a rare, newly recognized cause of acute kidney injury and significant but underdiagnosed complication of anticoagulation therapy.ARN occurs in patients taking oral anticoagulant therapy most often warfarin or a novel oral anticoagulant (NOAC).It is a Amplifiers potentially devastating disorder with serious renal consequences and increased all-cause mortality.Anticoagulant-related nephropathy presents as an acute kidney injury (AKI) in the setting of a supratherapeutic INR with profuse glomerular hemorrhage WALL DECOR seen as renal tubules filled with red cells and red cell casts on renal biopsy.
Being that millions of Americans are on warfarin, a thorough understanding and awareness of the clinical presentation, diagnosis, and therapeutic interventions are crucial to protecting the renal function, lowering all-cause mortality and optimizing treatment.Our goal is to provide education on a newly recognized form of AKI and significant but underdiagnosed complication of anticoagulation therapy.